SRP4503

FABP3 ヒト

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• 別名: H-FABP, M-FABP, 乳腺由来成長抑制因子, 心臓型脂肪酸結合タンパク質, 脂肪酸結合タンパク質(心臓), 脂肪酸結合タンパク質(筋)
• MDL番号: MFCD00285932
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in E. coli
• アッセイ: ≥98% (SDS-PAGE)
• フォーム: lyophilized
• 分子量: ~19 kDa
• 包装: pkg of 100 μg
• 保管条件: avoid repeated freeze/thaw cycles
• 不純物: endotoxin, tested
• NCBIアクセッション番号: P05413
• UniProtアクセッション番号: P05413
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... FABP3(2170)

詳細

詳細

Fatty acid binding proteins (FABPs) are intracellular proteins with a low molecular weight. They exhibit high affinity for small lipophilic ligands. FABP-3 is expressed in the skeletal muscle, heart, brain and brown adipose tissue. The gene encoding it is localized on human chromosome 1p35.[1][2]

生物化学的／生理学的作用

Studies suggest that fatty acid binding protein (FABPs) are involved in the uptake and metabolism of fatty acids, maintenance of cellular membrane fatty acids levels, intracellular trafficking, modulation of specific enzymes of lipid metabolic pathways, as well as in the modulation of cell growth and differentiation. FABPs have been associated with diabetes, obesity, atherosclerosis and brain function. FABP-3 has a role in glucose and lipid metabolism. It also modulates polysaturated fatty acid uptake and metabolism in neurons. The protein has been associated with schizophrenia, Down′s syndrome, Alzheimer′s disease and autism spectrum disorder.[1]

物理的形状

凍結乾燥品(ろ過滅菌済み、添加物不含)。

再構成

バイアルは、開封前に遠心してください。凍結融解の繰り返しは避けてください。

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable