PZ0284

PF-04753299

≥98%

• 別名: α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide, (+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, PF 04753299, PF-4753299
• 実験式（ヒル表記法）: C₁₈H₂₁NO₄S
• CAS番号: 1289620-49-0
• 分子量: 347.43
• MDL番号: MFCD22683864
• UNSPSCコード: 51111800
• PubChem Substance ID: 329823811
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98%
• フォーム: powder
• 色: white to light brown
• 溶解性: DMSO: 20 mg/mL, clear
• 保管温度: room temp
• SMILES記法: O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2
• InChI: 1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1
• InChI Key: GDYIQUFNICPYHF-GOSISDBHSA-N

詳細

生物化学的／生理学的作用

PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable