A6166

3-アセチルデオキシニバレノール

from Fusarium roseum

• 別名: 3α-アセチルボミトキシン, 3α-アセトキシ-7α,15-ジヒドロキシ-12,13-エポキシトリコテカ-9-エン-8-オン, 3-AcDON
• 実験式（ヒル表記法）: C₁₇H₂₂O₇
• CAS番号: 50722-38-8
• 分子量: 338.35
• NACRES: NA.77
• PubChem Substance ID: 24891062
• UNSPSC Code: 12352200
• MDL number: MFCD00135964
• Form: powder

特性

• biological source: Fusarium roseum
• Quality Segment: 200
• form: powder
• storage temp.: 2-8°C
• SMILES string: [H][C@]12O[C@]3([H])[C@@H](C[C@@](C)([C@]34CO4)[C@@]1(CO)[C@H](O)C(=O)C(C)=C2)OC(C)=O
• InChI: 1S/C17H22O7/c1-8-4-11-16(6-18,13(21)12(8)20)15(3)5-10(23-9(2)19)14(24-11)17(15)7-22-17/h4,10-11,13-14,18,21H,5-7H2,1-3H3/t10-,11-,13-,14-,15-,16-,17+/m1/s1
• InChI key: ADFIQZBYNGPCGY-HTJQZXIKSA-N

詳細

General description

3-Acetyldeoxynivalenol is a trichothecene mycotoxin, secreted by Fusarium species. It stimulates the activation of c-Jun N-terminal kinase (JNK)/ p38 mitogen-activated protein kinases and prevents protein synthesis. 3-Acetyldeoxynivalenol is a weak inducer of apoptosis.

Application

3-Acetyldeoxynivalenol has been used in a study to compare the ability of two fungi to improve wheat growth, decrease root colonization of Fusarium, and withstand mycotoxins. 3-Acetyldeoxynivalenol has also been used to induce and study anorexia in mice.

安全性情報

• ピクトグラム: GHS06
• 注意喚起語: Danger
• ハザードコード: H300,H311 + H331
• 注意事項: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation
• 保管分類: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 一体何が起きているの？: WGK 3
• 引火点 (F): Not applicable
• 引火点（°C）: Not applicable
• PPE（個人用保護具）: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges