RDD039

イミダゾール

for molecular biology, ≥99% (titration), free-flowing, Redi-Dri^™

• 別名: 1,3-ジアザ-2,4-シクロペンタジエン, グリオキサリン
• 実験式（ヒル表記法）: C₃H₄N₂
• CAS番号: 288-32-4
• 分子量: 68.08
• Beilstein: 103853
• MDL番号: MFCD00005183
• UNSPSCコード: 12352200
• NACRES: NA.21

特性

• グレード: for molecular biology
• 品質水準: 100
• 蒸気圧: <1 mmHg ( 20 °C)
• 製品種目: Redi-Dri^™
• アッセイ: ≥99% (titration)
• 形状: crystalline powder
• 品質: free-flowing
• pH: 6.2-7.8 (25 °C)
• pKa (25 °C): 6.95
• bp: 256 °C (lit.)
• mp: 88-91 °C (lit.)
• アプリケーション: diagnostic assay manufacturing
• その他の活性: DNase, RNase and protease, none detected
• SMILES記法: c1c[nH]cn1
• InChI: 1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)
• InChI Key: RAXXELZNTBOGNW-UHFFFAOYSA-N

詳細

詳細

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar.

アプリケーション

Imidazole has been used

• in the lysis, wash, and elution buffer for the purification of histidine tagged proteins
• in gradient for the purification of histidine tagged proteins using nickel affinity chromatography
• as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells

pH 6.2~7.8の範囲におけるバッファーとして優れています。

生物化学的／生理学的作用

Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).

特徴および利点

• Qualified for molecular biology applications, DNase, Rnase, and protease free
• Redi-Dri^™ packaging controls moisture, eliminating clumps
• Crystalline powder remains free-flowing and much easier to use
• Safer to handle and weigh out for routine use in lab
• Less waste, loss of drying, while maintaining high quality

その他情報

For additional information on our range of Biochemicals, please complete this form.

法的情報

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

安全性情報

• ピクトグラム: GHS08,GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H314,H360D
• 注意書き: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• 引火点(°F): 293.0 °F - closed cup
• 引火点(℃): 145 °C - closed cup