PHR1611

6-メルカプトプリン 一水和物

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 6-チオヒポキサンチン, 6-プリンチオール
• 実験式（ヒル表記法）: C₅H₄N₄S·H₂O
• CAS番号: 6112-76-1
• 分子量: 170.19
• Beilstein: 4012091
• EC Number: 200-037-4
• MDL番号: MFCD03854445
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823508
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 773; traceable to USP 1392002
• APIファミリー: mercaptopurine
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: O.S=C1NC=Nc2nc[nH]c12
• InChI: 1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2
• InChI Key: WFFQYWAAEWLHJC-UHFFFAOYSA-N
• 遺伝子情報: human ... PPAT(5471)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mercaptopurine is an anticancer and an immunosuppressive drug employed for the management of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn′s disease, etc. Its mode of action involves interference in the nucleic acid synthesis by the inhibition of purine metabolism.

アプリケーション

Mercaptopurine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, suspensions, and double drug liposomes by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC3476 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H301,H341,H361fd
• 注意書き: P202 - P264 - P280 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral - Muta. 2 - Repr. 2
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3