PHR1569

L-カルニチン 分子内塩

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: (−)-(R)-3-ヒドロキシ-4-(トリメチルアンモニオ)酪酸, ビタミンB_T
• 化学式: (CH₃)₃N⁺CH₂CH(OH)CH₂COO^-
• CAS番号: 541-15-1
• 分子量: 161.20
• Beilstein: 4292315
• EC Number: 208-768-0
• MDL番号: MFCD00038747
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823478
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. L0399900; traceable to USP 1359903
• APIファミリー: levocarnitine
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 197-212 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: C[N+](C)(C)C[C@H](O)CC([O-])=O
• InChI: 1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
• InChI Key: PHIQHXFUZVPYII-ZCFIWIBFSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Levocarnitine is a naturally available compound that plays a significant role in fatty acid oxidation and energy production in the human body. It is majorly found in skeletal and cardiac muscles of mammals and facilitates the transport of long chain fatty acids into mitochondria.[1]

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

カルニチンは、多くの哺乳類組織に存在する四級アミンです。エネルギ-代謝調節に関与する骨格筋や心臓に比較的高濃度で存在します。糖代謝を解糖からグリコ-ゲン貯蔵へ変換し、ミトコンドリアへの長鎖脂肪酸の輸送を促進します。輸送された長鎖脂肪酸はミトコンドリアでエネルギ-産生のために酸化されます。

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAB7787 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable