27102

クエン酸 一水和物

puriss., meets analytical specification of Ph. Eur., BP, USP, E330, 99.5-100.5% (based on anhydrous substance), grit

• 別名: 2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate
• 化学式: HOC(COOH)(CH₂COOH)₂ · H₂O
• CAS番号: 5949-29-1
• 分子量: 210.14
• Beilstein: 4018641
• EC Number: 201-069-1
• MDL番号: MFCD00149972
• UNSPSCコード: 12352100
• PubChem Substance ID: 57648219
• NACRES: NA.21

特性

• グレード: puriss.
• 品質水準: 200
• アッセイ: 99.5-100.5% (based on anhydrous substance)
• 形状: grit
• 品質: meets analytical specification of Ph. Eur., BP, USP, E330
• 不純物: residual solvents, complies; ≤0.0005% heavy metals (as Pb); 7.5-8.8% water (Karl Fischer)
• 強熱残分: ≤0.05% (as SO₄)
• pKa: (1) 3.13, (2) 4.76, (3) 6.4
• 微量陰イオン: chloride (Cl^-): ≤50 mg/kg; oxalate (as oxalic acid): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• 微量陽イオン: As: ≤1 mg/kg; Ca: ≤200 mg/kg; Cu: ≤10 mg/kg; Fe: ≤10 mg/kg; Hg: ≤1 mg/kg; Pb: ≤1 mg/kg; Zn: ≤10 mg/kg
• 適合性: complies for appearance of solution; complies for identity (IR); complies for reaction against H₂SO₄
• SMILES記法: OC(CC(O)(C(O)=O)CC(O)=O)=O.O
• InChI: 1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2
• InChI Key: YASYEJJMZJALEJ-UHFFFAOYSA-N

詳細

詳細

Citric acid monohydrate is an organic acid. Its molar enthalpy of solution in water has been reported to be Δ_solH_m (298.15K, m = 0.0203molkg^-1) = (29061 ± 123)Jmol^-1

アプリケーション

Citric acid monohydrate may be used in the diltiazem hydrochloride (drug) and melt extruded Eudragit RS PO (polymer) formulations. It improves the solubility of drug in the polymer matrix. It may be used to prepare citrate buffer for use in the intravital microscopic studies of adhesion and aggregation of platelets.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): 345.0 °F - closed cup
• 引火点(℃): 173.9 °C - closed cup
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves