Recognizes human Histamine Receptor 4 (HR4). The immunogen shows no significant sequence homology with other histamine receptors.
免疫原
A 17 amino acid peptide sequence within the cytoplasmic, C-terminus of human HR4 (Oda et al. 2000; Nakamura et al. 2000).
Epitope: C-terminus
アプリケーション
Research Category 炎症及び免疫
Research Sub Category 炎症及び自己免疫疾患
Anti-Histamine Receptor 4 Antibody, C-terminus detects level of Histamine Receptor 4 & has been published & validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using ECL.
ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well (Catalog number AG217).
Optimal working dilutions must be determined by the end user.
物理的形状
Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA.
保管および安定性
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
American journal of physiology. Renal physiology, 325(1), F105-F120 (2023-05-25)
Histamine is involved in the regulation of immune response, vasodilation, neurotransmission, and gastric acid secretion. Although elevated histamine levels and increased expression of histamine metabolizing enzymes have been reported in renal disease, there is a gap in knowledge regarding the
Functional role of histamine receptors in the renal cortical collecting duct cells.
Sudarikova, et al.
American Journal of Physiology. Cell Physiology, 322, C775-C786 (2023)