572201

Streptozotocin

An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.

• 別名: Streptozotocin, 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
• 実験式（ヒル表記法）: C₈H₁₅N₃O₇
• CAS番号: 18883-66-4
• 分子量: 265.22
• MDL番号: MFCD00006607
• UNSPSCコード: 12352103

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: crystalline solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: off-white to pale yellow
• 溶解性: water: soluble
• 微量陽イオン: heavy metals: ≤5 ppm
• 輸送温度: ambient
• 保管温度: −20°C
• InChI: 1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1
• InChI Key: ZSJLQEPLLKMAKR-GKHCUFPYSA-N

詳細

詳細

An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells. A diabetogenic agent.

An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

再構成

Unstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).

その他情報

Kroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler376, 179.
Kwon, N.S., et al. 1994. FASEB J.8, 529.
Rasschaert, J., et al. 1992. Endocrinology130, 3522.
Bennett, R.A. and Pegg, A.E. 1981. Cancer Res.41, 2786.
Yamamoto, H., et al. 1981. Nature294, 284.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS08
• シグナルワード: Warning
• 危険有害性情報: H228,H341,H351
• 注意書き: P202 - P210 - P240 - P241 - P280 - P308 + P313
• 危険有害性の分類: Carc. 2 - Flam. Sol. 2 - Muta. 2
• 保管分類コード: 4.1B - Flammable solid hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable