5.04913

Aniracetam

• 別名: Aniracetam, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet, Memodrin, Referan, Memodrin, Referan, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet
• 実験式（ヒル表記法）: C₁₂H₁₃NO₃
• CAS番号: 72432-10-1
• 分子量: 219.24
• MDL番号: MFCD00153767
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• アッセイ: ≥99% (HPLC)
• 品質水準: 100
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: white
• 溶解性: DMSO: 100 mM
• 保管温度: 2-8°C
• SMILES記法: N2(CCCC2=O)C(=O)c1ccc(cc1)OC
• InChI: 1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3
• InChI Key: ZXNRTKGTQJPIJK-UHFFFAOYSA-N

詳細

詳細

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

生物化学的／生理学的作用

Primary Target
AMPA receptors

警告

Toxicity: Standard Handling (A)

その他情報

Koliaki, C., et al. 2012. CNS Neuroscience & Therapeutics.18, 302.
Lynch, G., et al. 2011. Pharmacol. Biochem. Behav.99, 116.
Nakamura, K., et al. 2001. Eur. J. Pharmacol.420, 33.
Ito, I. et al., 1990. J. Physiol.424, 553.
Isaacson et al., 1991. PNAS.88, 1093.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable