442630-M

GMBS

• 別名: GMBS, N-γ-Maleimidobutyryloxysuccinimide
• 実験式（ヒル表記法）: C₁₂H₁₂N₂O₆
• CAS番号: 80307-12-6
• 分子量: 280.23
• MDL番号: MFCD00036817
• UNSPSCコード: 12161500
• NACRES: NA.24

特性

• アッセイ: ≥90% (HPLC)
• 品質水準: 100
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 保管温度: −20°C
• SMILES記法: N2(C(=O)CCC2=O)OC(=O)CCCN1C(=O)C=CC1=O
• InChI: 1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
• InChI Key: PVGATNRYUYNBHO-UHFFFAOYSA-N

詳細

詳細

Heterobifunctional reagent useful for preparation of conjugates such as secondary antibodies and β-galactosidase for EIA procedures or for immobilizing enzymes on solid supports.

N-γ-maleimidobutyryloxysuccinimide ester (GMBS) is an aliphatic crosslinker for immunotoxins (IT).(1) It is used for the generation of conjugated Poly-γ-D-glutamic acid.

アプリケーション

GMBS is suitable for use:

• as a hetero-bifunctional cross-linking reagent for the immobilization of neural adhesion molecule L1 onto silicon dioxide surface[1]
• for the crosslinking of biochips with functionalized gold nanoparticles[2]
• for coating salinized capillary tube prior to neutravidin treatment in biosensor sandwich immunoassay[3]

警告

Toxicity: Irritant (B)

再構成

Reconstitute to 10 mg/ml in tetrahydrofuran or DMSO. Add 1 ml of this stock solution dropwise, with stirring, to 10 ml of 20 mM phosphate buffer.

その他情報

Rusin, K.M., et al. 1992. Biosens. Bioelectron. 7, 367.
Kitagawa, T., et al. 1983. J. Biochem. 94, 1160.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable