345736

Ganglioside GD_1a, Disialo, Diammonium Salt, Bovine Brain

Useful as a differentiation marker of tumor cell growth.

• 別名: Ganglioside GD_1a, Disialo, Diammonium Salt, Bovine Brain, Cer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
• 実験式（ヒル表記法）: C₈₄H₁₄₆N₄O₃₉ · 2NH₄
• 分子量: 1872.14
• UNSPSCコード: 12352211
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (TLC)
• フォーム: lyophilized
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 溶解性: DMSO: soluble; chloroform/methanol (2:1): soluble
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

Disialoganglioside prepared from bovine gray matter. Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM₁ by bacterial and mammalian sialidases without detergent or bile salts. One mole yields 2 moles of sialic acid by thiobarbituric acid assay. The molecular weight is based on stearoyl-18:0.



Note: This product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock.

Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM₁ by bacterial and mammalian neuraminidases without detergent or bile salts. Note: the moleculare weight is based on on stearoyl-18:0.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Protein kinase C

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

調製ノート

For use in aqueous systems, dissolve in a small amount of DMSO and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions may be filter sterilized.

再構成

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

その他情報

Longee, D.C., et al. 1991. Acta Neuropathologica82, 45.
Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA84, 2911.
Kundu, S.K., and Scott, D.D. 1982. J. Chromato.232, 19.
Wakomari, S. 1981. Annu. Rev. Biochem.50, 733.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable