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Merck
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主要文書

33-125

Sigma-Aldrich

PIP5-Kinase HTRF Assay

The PIP5 Kinase HTRF Assay kit provides a method for assaying PI(4)P-5 kinases in a homogenous 384 well format. Suitable for screening of potential inhibitors of these enzymes.

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.54
現在、価格および在庫状況を閲覧できません。

品質水準

交差性

mouse, human

メーカー/製品名

HTRF®
Upstate®

テクニック

activity assay: suitable (kinase)

NCBIアクセッション番号

検出方法

fluorometric (HTRF)

輸送温度

dry ice

アプリケーション

Research Category
アポトーシス及び癌
Research Sub Category
腫瘍学
The PIP5 Kinase HTRF Assay kit provides a method for assaying PI(4)P-5 kinases in a homogenous 384 well format. Suitable for screening of potential inhibitors of these enzymes.
Used to detect/quantify: PIP5 Kinase

生物化学的/生理学的作用

Target Sub-Family: PI3K/PI4K

包装

Kit capacity: 384 wells

構成

Reaction Buffer (4X)

DM A Detection Reagent

DM C Detection Reagent

DM E Detection Reagent

Phosphatidylinositol 4-phosphate (1mM)

Phosphatidylserine (1mM)

Stop Reagent D

保管および安定性

12 months at -70°C

法的情報

HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

保管分類コード

10-13 - German Storage Class 10 to 13


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文書ライブラリで、最近購入した製品の文書を検索できます。

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Yuxun Zhang et al.
The Journal of biological chemistry, 292(24), 10239-10249 (2017-05-02)
SIRT5 is a lysine desuccinylase known to regulate mitochondrial fatty acid oxidation and the urea cycle. Here, SIRT5 was observed to bind to cardiolipin via an amphipathic helix on its N terminus. In vitro, succinyl-CoA was used to succinylate liver
Thuc T Le et al.
Journal of lipid research, 54(4), 1044-1057 (2013-01-29)
We report in this study an intrinsic link between pyrimidine metabolism and liver lipid accumulation utilizing a uridine phosphorylase 1 transgenic mouse model UPase1-TG. Hepatic microvesicular steatosis is induced by disruption of uridine homeostasis through transgenic overexpression of UPase1, an
Marco Spinazzi et al.
Nature protocols, 7(6), 1235-1246 (2012-06-02)
The assessment of mitochondrial respiratory chain (RC) enzymatic activities is essential for investigating mitochondrial function in several situations, including mitochondrial disorders, diabetes, cancer, aging and neurodegeneration, as well as for many toxicological assays. Muscle is the most commonly analyzed tissue

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