218745

Caspase Inhibitor III

The Caspase Inhibitor III, also referenced under CAS 634911-80-1, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.

• 別名: Caspase Inhibitor III, Boc-D-FMK
• 実験式（ヒル表記法）: C₁₁H₁₈FNO₅
• CAS番号: 634911-80-1
• 分子量: 263.26
• MDL番号: MFCD04038181
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• フォーム: semisolid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated
• 色: off-white
• 溶解性: DMSO: 5 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: FCC(=O)C(NC(=O)OC(C)(C)C)CC(=O)OC
• InChI: 1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)
• InChI Key: MXOOUCRHWJYCAL-UHFFFAOYSA-N

詳細

詳細

A broad-spectrum cell-permeable and irreversible caspase inhibitor.

A cell-permeable, irreversible, broad-spectrum caspase inhibitor.

生物化学的／生理学的作用

Cell permeable: yes

Primary Target
broad spectrum caspase

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

シーケンス

Boc-Asp(OMe)-CH₂F*

再構成

Following reconstitution aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 4 months at 4°C or for up to 1 year at -20°C.

アナリシスノート

single spot by TLC

その他情報

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
D’Mello, S.R., et al. 1998. J. Neurochem. 70, 1809.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable