for use with Viable Air Samplers (1.09191) for use with Viable Air Samplers (1.09194) for use with Viable Air Samplers (1.17103) for use with Viable Air Samplers (1.17274) for use with Viable Air Samplers (1.17275)
A highly potent, selective, and orally bioavailable non-xanthine adenosine A2A receptor antagonist (Ki = 800 pM for human adenosine A2AR stably expressed in HEK-293 cells). Does not exhibit any significant antagonistic activity in A1, A2B (Ki = 255 nM and 50 nM, respectively in human adenosine receptors stably expressed in CHO cells) or in A3R (Ki >10 µM in human A3R stably expressed in HEK-293 cells). Shown to have a protective effect against beta-amyloid peptide toxicity.
A highly potent, selective, non-xanthine adenosine A2A receptor antagonist (Ki = 800 pM for human adenosine A2AR stably expressed in HEK-293 cells).
生物化学的／生理学的作用
Primary Target A2A
Reversible: yes
警告
Toxicity: Standard Handling (A)
再構成
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
その他情報
Poucher, S. M., et al. 1995. Brit. J. Pharmacol. 115, 1096. Ongini, E. et al. 1999. Naunyn Schmiedebergs Arch Pharmacol. 359, 7.
Keddie, J. et al. 1996, Eur Journ Pharm. 301, 107.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
