1.02307

α-Chymotrypsin from bovine pancreas

cryst. lyophilized 350 U/mg for biochemistry

• UNSPSCコード: 12352204
• NACRES: NA.21

特性

• 形状: solid
• 有効性: >4000 mg/kg LD₅₀, oral (rat)
• pH: 3-5 (10 g/L in H₂O)
• 保管温度: 2-8°C

詳細

詳細

α-Chymotrypsin (CT) is a member of the S1 family. It comprises a catalytic triad system including aspartate, histidine, and serine. It is produced by chymotrypsinogen in the pancreas and then secreted into the digestive tract.

アプリケーション

α-Chymotrypsin has been used to study its adsorption characteristics on solid/liquid interfaces under varying adsorption conditions.

生物化学的／生理学的作用

α-Chymotrypsin (CT) closely denotes a group of digestive enzymes (trypsin, elastase) that hydrolyzes polypeptide chains. The catalytic triad system works together to regulate the nucleophilicity of the serine residue in catalysis. CT shows a capability to catalyze nonconventional synthetic reactions in water-miscible organic media. Additionally, it is also used as a tool in comparative studies of water-miscible and water-immiscible solvents.

特徴および利点

• Easily obtainable due to small size
• Relatively stable

アナリシスノート

Appearance (description):lyophilisate
Appearance (colour):slightly yellowish
Activity (ATEE, pH 8.0, 25 °C):≥ 350 U/mg
Spec. activity (calc. on protein):ca. 400

安全性情報

• ピクトグラム: GHS07,GHS08,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302 - H315 - H319 - H334 - H335 - H400
• 注意書き: P261 - P273 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1