STAT5B (signal transducers and activators of transcription 5b) controls the expression of early response genes and takes part in cytokine signaling. Studies have linked this protein to the inhibition of NFkappaB-mediated signaling. Additional studies have shown an association of STAT5B with regulation of lactation and growth, performance, and control of adipocyte function. Constitutively active STAT5B expression is often observed in a large number of leukemia’s and solid tumors.
特異性
This antibody recognizes STAT5B acetylated at Lys694.
免疫原
Epitope: Acetylated Lys694
KLH-conjugated linear peptide corresponding to mouse STAT5B acetylated at Lys694.
アプリケーション
Anti-acetyl STAT5B (Lys694) Antibody is a Rabbit Polyclonal Antibody for detection of acetyl STAT5B (Lys694) also known as Signal transducer & activator of transcription 5B & has been validated in DB & WB.
品質
Evaluated by Dot Blot in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.
Dot Blot Analysis: 1 µg/mL of this antibody detected STAT5B in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.
ターゲットの説明
90 kDa calculated
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.