O-030

オキシホルホン-3-β-D-グルクロニド 溶液

100 μg/mL in methanol: water (1:1), ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₂₃H₂₇NO₁₀
• CAS番号: 770735-01-8
• 分子量: 477.46
• MDL番号: MFCD16294834
• UNSPSCコード: 41116107
• PubChem Substance ID: 329818838
• NACRES: NA.24

特性

• グレード: certified reference material
• 形状: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 100 μg/mL in methanol: water (1:1)
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: 2-8°C
• SMILES記法: CN1CC[C@]23[C@H]4Oc5c(O[C@@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O)C(O)=O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35
• InChI: 1S/C23H27NO10/c1-24-7-6-22-13-9-2-3-11(32-21-16(28)14(26)15(27)18(34-21)20(29)30)17(13)33-19(22)10(25)4-5-23(22,31)12(24)8-9/h2-3,12,14-16,18-19,21,26-28,31H,4-8H2,1H3,(H,29,30)/t12-,14+,15+,16-,18+,19+,21-,22+,23-/m1/s1
• InChI Key: ILRLBQVIWURYLX-WUDROUKASA-N

詳細

詳細

オキシモルフォン-3ß-D-グルクロニドの認証Snap-N-Spike^®溶液。痛みのための処方薬のモニタリング、臨床毒性検査、医薬品研究、法医学分析、または尿中薬物検査などのさまざまなGC/MSアプリケーションやLC/MSアプリケーションにおける使用に適しています。オキシモルフォン-3ß-D-グルクロニドは、尿中と血漿中のオキシモルフォンの主な代謝産物です。オキシモルフォンはOpana^®、Numorphan^®、およびNumorphoneなどの商品名で販売されており、中等度から重度の疼痛の緩和に適応される麻薬性鎮痛剤です。

アプリケーション

• Validation of a thin-layer chromatography/densitometry method for the characterization of invertase activity.: This study validated a TLC-densitometric method using Silica gel 60 F₂₅₄ for the characterization of invertase activity, demonstrating the technique′s robustness and reliability in analyzing enzyme activity (Ferey et al., 2016).


• Stability-Indicating TLC-Densitometric and HPLC Methods for the Simultaneous Determination of Piracetam and Vincamine in the Presence of Their Degradation Products.: This research developed and validated stability-indicating methods using TLC-densitometry with Silica gel 60 F₂₅₄ and HPLC for the simultaneous determination of piracetam and vincamine, highlighting the methods′ precision and sensitivity in the presence of degradation products (Ahmed et al., 2016).


• TLC densitometric method for the preliminary evaluation of fucoxanthin-based products.: This paper presented a TLC-densitometric method utilizing Silica gel 60 F₂₅₄ for the analysis of fucoxanthin in commercial products, showing its effectiveness for preliminary quality assessment of these products (Piovan et al., 2014).


• Modulation of the cardiac membrane-bound cyclic nucleotide phosphodiesterase: inhibition due to a contamination of TLC purified S-adenosyl-L-[methyl-3H] methionine by Zn++ ions.: This study investigated the inhibition of cardiac membrane-bound cyclic nucleotide phosphodiesterase by Zn++ ions, which were contaminants in TLC purified S-adenosyl-L-[methyl-3H] methionine using Silica gel 60 F₂₅₄, emphasizing the need for careful sample preparation in biochemical assays (Dubois et al., 1985).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Numorphan is a registered trademark of Endo Pharmaceuticals Inc.

Opana is a registered trademark of Endo Pharmaceuticals Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H226,H301 + H311 + H331,H370
• 注意書き: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3 - STOT SE 1
• ターゲットの組織: Eyes,Central nervous system
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 75.2 °F - closed cup
• 引火点(℃): 24 °C - closed cup