A-002

(±)-Amphetamine-d₅ (deuterium label on ring) solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₉D₅H₈N
• CAS番号: 65538-33-2
• 分子量: 140.24
• EC Number: 200-659-6
• MDL番号: MFCD00673255
• UNSPSCコード: 41116107
• PubChem Substance ID: 329770563
• NACRES: NA.24

特性

• グレード: certified reference material
• 形状: liquid
• 特徴: SNAP-N-SPIKE^®. SNAP-N-SHOOT^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• 濃度: 100 μg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: CC(N)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]
• InChI: 1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/i2D,3D,4D,5D,6D
• InChI Key: KWTSXDURSIMDCE-VIQYUKPQSA-N

詳細

詳細

Amphetamine, a central nervous system stimulant, belongs to the phenethylamine clas. It is found in ADHD-treatment drugs such as Adderall^®, Vyvanse^®, and ProCentra^®. It is also used for the treatment of narcolepsy. Because of its stimulant effect, amphetamine is used recreationally as a performance-enhancer and illicit drug. This stable-labeled internal standard is suitable for quantitation of amphetamine levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or sports testing.

アプリケーション

• Amphetamine-d5 solution as a mass spectrometry internal standard: The deuterium-labeled amphetamine (amphetamine-d5) serves as a precise internal standard for mass spectrometry, enhancing the accuracy of quantitative analyses in forensic toxicology and pharmaceutical testing. This application is crucial for identifying and quantifying amphetamine in biological samples, as demonstrated in a method developed for detecting psychoactive drugs (Barone et al., 2023).


• Stable isotope-labeled amphetamine for pharmaceutical research: Amphetamine-d5 is employed in pharmaceutical research to investigate the metabolic pathways of amphetamines. Its stable isotopic label allows for the tracking of amphetamine metabolites in complex biological matrices, offering insights into drug metabolism and pharmacokinetics (Alhazmi et al., 2020).


• Deuterated amphetamine in analytical chemistry: As a high-purity analytical reference material, amphetamine-d5 is used to calibrate and validate chromatographic and mass spectrometric methods. This ensures the reliability and reproducibility of analytical assays in both clinical and forensic settings, critical for drug monitoring and therapeutic drug management (Mohamed et al., 2016).

法的情報

Adderall is a registered trademark of Richwood Pharmaceutical Company, Inc.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

ProCentra is a registered trademark of Outlook Pharmaceuticals, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Vyvanse is a registered trademark of Shire, LLC

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup