LM2001

Sphinganine (d17:0)

heptadecasphinganine, ethanol solution

• 別名: (2S,3R)-2-aminoheptadecane-1,3-diol, C17 Sphinganine
• 実験式（ヒル表記法）: C₁₇H₃₇NO₂
• CAS番号: 32164-02-6
• 分子量: 287.48
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• フォーム: ethanol solution
• 包装: pkg of 1 × 1 mL (LM2001-1EA)
• メーカー／製品名: Avanti Research^™ - A Croda Brand LM2001
• 濃度: ~10 μg/mL (Refer to C of A for lot specific concentration.)
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCC
• InChI: 1S/C17H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h16-17,19-20H,2-15,18H2,1H3/t16-,17+/m0/s1
• InChI Key: KFQUQCFJDMSIJF-DLBZAZTESA-N

詳細

詳細

Sphinganine, also known as dihydrosphingosine is a sphingoid base precursor of ceramide.[1][2]

アプリケーション

Sphinganine (d17:0) has been used as a constituent of the internal standard mixture in mass spectrometry.[3]

生物化学的／生理学的作用

Sphinganine (SPA) is involved in sphingolipid biosynthesis pathway. It is free from the double bond.[4] SPA has an ability to inhibit the activity of protein kinase c. SPA accumulation enables fumonisin B1 to stimulate apoptosis.[5]

Sphinganine plays a vital role in cell regulation, cell growth modulation and signal transmission, functioning as an inhibitor of protein kinase C.[2] It inhibits the low-density lipoprotein-induced esterification of cholesterol by the blockage of post-lysosomal cholesterol transport.[6] Sphinganine is useful as a biomarker for studying microbial diversity.[7]

包装

2 mL Amber Glass Sealed Ampule (LM2001-1EA)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H319
• 注意書き: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Flam. Liq. 2
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 55.4 °F - closed cup
• 引火点(℃): 13.0 °C - closed cup