870865P

BMP22

Avanti Research^™ - A Croda Brand, powder

• 別名: 4-pentadecylbenzylphosphonic acid
• 実験式（ヒル表記法）: C₂₂H₃₉O₃P
• CAS番号: 1306684-90-1
• 分子量: 382.52
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• アッセイ: 99% (TLC)
• 形状: powder
• 包装: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 脂質タイプ: bioactive lipids
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1

詳細

詳細

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

生物化学的／生理学的作用

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

包装

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable