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アッセイ
>99% (TLC)
フォーム
powder
包装
pkg of 1 × 1 g (850338P-1g)
pkg of 1 × 10 g (850338P-10g)
メーカー／製品名
Avanti Research™ - A Croda Brand 850338P
輸送温度
dry ice
保管温度
−20°C
SMILES記法
[P](=O)([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCCCC
InChI
1S/C19H42NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-23-25(21,22)24-19-17-20(2,3)4/h5-19H2,1-4H3
InChI Key
BETUMLXGYDBOLV-UHFFFAOYSA-N
詳細
MAPCHO™-14 is a fos-choline-based zwitterionic detergent.[1]
Tetradecylphosphocholine is a structural analog of myristoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification. It has been used as a helper lipid for in vitro and in vivo gene transfer, and it has been shown to have some anticancer activity.
アプリケーション
MAPCHO™-14 has been used as a supplement in extraction buffer (RIPA buffer).[2]
生物化学的／生理学的作用
Fos-choline-14 (N-tetradecylphosphocholine) is mainly used for solubilization and purification of proteins.[1]
包装
20 mL Clear Glass Screw Cap Vial (850338P-1g)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (850338P-10g)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
850338P-1G:
850338P-10G:
850338P-BULK:
850338P-VAR:
最新バージョンのいずれかを選択してください：
Brian L Cook et al.
PloS one, 3(8), e2920-e2920 (2008-08-07)
In order to begin to study the structural and functional mechanisms of olfactory receptors, methods for milligram-scale purification are required. Here we demonstrate the production and expression of a synthetically engineered human olfactory receptor hOR17-4 gene in a stable tetracycline-inducible
Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line
Cook BL, et al.
Testing, 3(8), e2920-e2920 (2008)
Pernille M Christensen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(6), 2351-2359 (2016-03-10)
Apolipoprotein M (ApoM) transports sphingosine-1-phosphate (S1P) in plasma, and ApoM-deficient mice (Apom(-/-)) have ∼50% reduced plasma S1P levels. There are 5 known S1P receptors, and S1P induces adherens junction formation between endothelial cells through the S1P1 receptor, which in turn
Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1
Christensen PM, et al.
Faseb Journal, 30(6), 2351-2359 (2016)
Gregory Vernier et al.
Protein science : a publication of the Protein Society, 18(9), 1882-1895 (2009-07-18)
Proteolytically activated Protective Antigen (PA) moiety of anthrax toxin self-associates to form a heptameric ring-shaped oligomer (the prepore). Acidic pH within the endosome converts the prepore to a pore that serves as a passageway for the toxin's enzymatic moieties to
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