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安全性情報

810227P

Avanti

C12-NBD Lactosyl Ceramide

Avanti Research - A Croda Brand 810227P, powder

別名:

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-lactosyl-β1-1′-sphingosine

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About This Item

実験式(ヒル表記法):
C48H81N5O16
CAS番号:
分子量:
984.18
MDL番号:
UNSPSCコード:
12352211
NACRES:
NA.25
現在、価格および在庫状況を閲覧できません。

アッセイ

>99% (TLC)

フォーム

powder

包装

pkg of 1 × 50 μg (810227P-50ug)

メーカー/製品名

Avanti Research - A Croda Brand 810227P

輸送温度

dry ice

保管温度

−20°C

関連するカテゴリー

詳細

C12-NBD Lactosyl ceramide is a fluorescent analog of biologically available compound lactosyl ceramide.[1] Lactosyl ceramideis generally present on neutrophils and macrophages.[2]

生物化学的/生理学的作用

Lactosyl ceramide is the major precursor for synthesis of various glycosphingolipids like oligoglycosylceramides and gangliosides. It is an important signaling molecule that is involved in adhesion, migration, cell proliferation and angiogenesis. [2][3][4][5] Lactosyl ceramide is vital for osteoclastogenesis mediated by macrophage-colony stimulating factor.[6]

包装

5 mL Amber Glass Screw Cap Vial (810227P-50ug)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

810227P-500UG:
810227P-BULK:
810227P-1MG:
810227P-VAR:
810227P-50UG:


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試験成績書(COA)

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以前この製品を購入いただいたことがある場合

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文書ライブラリにアクセスする

T Iwamoto et al.
The Journal of biological chemistry, 276(49), 46031-46038 (2001-10-11)
Glycosphingolipids and their metabolites play important roles in a variety of biological processes. Several signal molecules are localized in a glycolipid-enriched microdomain on the cell surface, and their signals are regulated by the glycolipid composition. However, the function of glycolipids
S Hakomori et al.
Journal of biochemistry, 118(6), 1091-1103 (1995-12-01)
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been implicated as playing major roles in cellular interactions and control of cell proliferation in multicellular organisms. These functional roles have been partially clarified through two types
W I Weis et al.
Annual review of biochemistry, 65, 441-473 (1996-01-01)
Lectins are responsible for cell surface sugar recognition in bacteria, animals, and plants. Examples include bacterial toxins; animal receptors that mediate cell-cell interactions, uptake of glycoconjugates, and pathogen neutralization; and plant toxins and mitogens. The structural basis for selective sugar
Subroto Chatterjee et al.
Biochimica et biophysica acta, 1780(3), 370-382 (2007-12-14)
Although lactosylceramide (LacCer) plays a pivotal role in the biosynthesis of nearly all the major glycosphingolipids, its function in regulating cellular function has begun to emerge only recently. Our current opinion is that several physiologically critical molecules such as modified/oxidized
F Pincet et al.
Biophysical journal, 80(3), 1354-1358 (2001-02-27)
Carbohydrate-carbohydrate interactions are rarely considered in biologically relevant situations such as cell recognition and adhesion. One Ca(2+)-mediated homotypic interaction between two Lewis(x) determinants (Le(x)) has been proposed to drive cell adhesion in murine embryogenesis. Here, we confirm the existence of

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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