QBD10109

Acid-dPEG^®₅-NHS ester

• 別名: Polyethylene glycol
• 実験式（ヒル表記法）: C₁₈H₂₉NO₁₁
• 分子量: 435.42
• MDL番号: MFCD27952888
• UNSPSCコード: 12352106
• PubChem Substance ID: 329823879
• NACRES: NA.22

特性

• アッセイ: >90%
• 形状: solid or viscous liquid
• 反応適合性: reagent type: cross-linking reagent; reactivity: amine reactive
• 官能基: NHS ester; carboxylic acid
• ポリマー構造: shape: linear; functionality: heterobifunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: OC(CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O

詳細

特徴および利点

Acid-dPEG^®₅-NHS ester allows conjugation to two different moieties, each containing free amines. Because the single molecular weight dPEG^® spacers contain an N-hydroxysuccinimide ester only on one end of the spacer, greater control of the conjugation reaction can be maintained. The free acid end of the spacer can be left unreacted to modify the surface properties of the molecule to which it is conjugated, or the free acid end can be activated and conjugated to a different group at a later time. The dPEG^® spacers provide precise spacing/distance control, and the dPEG^® itself provides the well-known benefits of increased water solubility; decreased immunogenicity; protection from proteolysis; increased hydrodynamic volume; and increased serum half-life.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable