802255

8-Amino-5-methoxyquinoline

95%

• 別名: 5-Methoxy-8-quinolinamine, Chen Auxilliary, MQ, Gong Chen Auxiliary, MQ Auxiliary
• 実験式（ヒル表記法）: C₁₀H₁₀N₂O
• CAS番号: 30465-68-0
• 分子量: 174.20
• MDL番号: MFCD01593679
• UNSPSCコード: 12352100
• PubChem Substance ID: 329768733
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 95%
• フォーム: powder
• mp: 90-95 °C
• SMILES記法: NC1=CC=C(OC)C2=CC=CN=C21
• InChI: 1S/C10H10N2O/c1-13-9-5-4-8(11)10-7(9)3-2-6-12-10/h2-6H,11H2,1H3
• InChI Key: MFLLTRMMFHENCM-UHFFFAOYSA-N

詳細

詳細

8-Amino-5-methoxyquinoline is a substituted quinoline derivative that can be prepared using 5-chloro-2-nitroaniline as a starting material. It can act as an easily removable directing group and also mediate C-H activation.[1] These properties have been useful for synthesizing isomeric dibenzoxazepinones and complex pyrrolidinones from compounds containing 8-amino-5-methoxyquinoline moiety.[1][2]

アプリケーション

The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp³)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature.

その他情報

Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated γ C(sp³)-H bonds

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable