748188

Bis(2,2,6,6-tetramethylpiperidinyl)zinc, lithium chloride, magnesium chloride complex solution

in THF/toluene

• 化学式: C₁₈H₃₆N₂Zn · xMgCl₂ · xLiCl
• UNSPSCコード: 12352103
• NACRES: NA.22

特性

• フォーム: liquid
• 組成: Bis(2,2,6,6-tetramethylpiperidinyl)zinc, ~12 wt. % ; LiCl, 2-4% ; MgCl₂, 6-9% ; THF/toluene, ca. 90:10 (solvent)
• 濃度: in THF/toluene
• 密度: 0.991 g/mL at 25 °C

詳細

詳細

Bis(2,2,6,6-tetramethylpiperidinyl)zinc,lithium chloride, magnesium chloride complex solution is an organozinc reagentextensively used in C-C bond forming,Negishi coupling, Michael additions, Cu(I)-promoted reactions, and electrophilic amination reactions.

アプリケーション

Bis(2,2,6,6-tetramethylpiperidinyl)zinc, lithium chloride, magnesium chloride complex solution can be used as a base for the:

• Regioselective zincation of pyridines and related azines to synthesize zincated pyridines and azines.(1)
• Chemoselective direct zincation of arenes and heteroarenes to synthesize polyfunctional aryl and heteroaryl zinc reagents.
• Regioselective zincation of thiazoles to synthesize zincated thiazoles, which readily reacts with various electrophiles to form highly functionalized thiazoles.

安全性情報

• ピクトグラム: GHS02,GHS08,GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H314,H335,H336,H351,H361d
• 注意書き: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 3
• ターゲットの組織: Central nervous system, Respiratory system
• 補足的ハザード: EUH014,EUH019
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 5.0 °F
• 引火点(℃): -15 °C