511943

1-アセチル-4-(4-ヒドロキシフェニル)ピペラジン

98%

• 実験式（ヒル表記法）: C₁₂H₁₆N₂O₂
• CAS番号: 67914-60-7
• 分子量: 220.27
• EC Number: 267-744-8
• MDL番号: MFCD00044905
• UNSPSCコード: 12352100
• PubChem Substance ID: 24873593

特性

• アッセイ: 98%
• mp: 180-185 °C (lit.)
• SMILES記法: CC(=O)N1CCN(CC1)c2ccc(O)cc2
• InChI: 1S/C12H16N2O2/c1-10(15)13-6-8-14(9-7-13)11-2-4-12(16)5-3-11/h2-5,16H,6-9H2,1H3
• InChI Key: AGVNLFCRZULMKK-UHFFFAOYSA-N

詳細

詳細

1-Acetyl-4-(4-hydroxyphenyl)piperazine (AHPP), a piperazine derivative, is a structural analog of acetaminophen.[1] Its multi-step preparation using bis-(2-chloroethyl)amine hydrochloride and p-aminophenol as starting materials has been reported.2[2]

アプリケーション

1-Acetyl-4-(4-hydroxyphenyl)piperazine may be used in the preparation of 1-acetyl-4-(4-octadecyloxyphenyl)piperazine.[3] It may also be used in the multi-step synthesis of ketoconazole,[4] its 1,2,4-triazole and thiazole analogs.[5]

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves