49510

L-グルタミン酸 γ-ベンジルエステル

≥99.0% (T)

• 別名: L-グルタミン酸 5-ベンジルエステル
• 化学式: C₆H₅CH₂OCOCH₂CH₂CH(NH₂)COOH
• CAS番号: 1676-73-9
• 分子量: 237.25
• Beilstein: 1885646
• EC Number: 216-826-1
• MDL番号: MFCD00002633
• UNSPSCコード: 12352209
• PubChem Substance ID: 57651200
• NACRES: NA.22

特性

• アッセイ: ≥99.0% (T)
• 光学活性: [α]20/D +19±2°, c = 1% in acetic acid
• 反応適合性: reaction type: solution phase peptide synthesis
• mp: 181-182 °C (lit.)
• アプリケーション: peptide synthesis
• 保管温度: 2-8°C
• SMILES記法: N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O
• InChI: 1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1
• InChI Key: BGGHCRNCRWQABU-JTQLQIEISA-N

詳細

アプリケーション

L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:

• Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.
• Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.
• Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)