EDC and EDAC are both abbreviations for N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide. While a detailed procedure for conjugating haptens (such as peptides) to carrier proteins such as Bovine Serum Albumin (BSA) is not available, the EDC is typically used at a 5 to 10-fold molar excess with respect to the hapten concentration in the reaction mix. Note that EDC hydrochloride (e.g., Products E6383, E7750 and 03450) is more commonly used as a coupling agent than EDC free base (Product 39391).
39391
N-(3-ジメチルアミノプロピル)-N′-エチルカルボジイミド
≥97.0% (T), for peptide synthesis
別名:
N-エチル-N′-(3-ジメチルアミノプロピル)カルボジイミド, EDC, WSC
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10 ML
￥10,800
50 ML
￥49,100
About This Item
実験式（ヒル表記法）:
C8H17N3
CAS番号:
分子量:
155.24
Beilstein:
507429
EC Number:
MDL番号:
UNSPSCコード:
12352116
PubChem Substance ID:
NACRES:
NA.22
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製品名
N-(3-ジメチルアミノプロピル)-N′-エチルカルボジイミド, ≥97.0% (T)
品質水準
アッセイ
≥97.0% (T)
フォーム
liquid
反応適合性
reaction type: Coupling Reactions
屈折率
n20/D 1.461
密度
0.877 g/mL at 20 °C (lit.)
アプリケーション
peptide synthesis
官能基
amine
保管温度
−20°C
SMILES記法
CCN=C=NCCCN(C)C
InChI
1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3
InChI Key
LMDZBCPBFSXMTL-UHFFFAOYSA-N
詳細
N-(3-ジメチルアミノプロピル)-N′-エチルカルボジイミドは、カルボキシル基を活性化することにより、アミンとカップリングしてアミドを生成するカルボジイミドカップリング反応において、N-ヒドロキシスクシンイミド（NHS）と組み合わせて一般的に使用されます。[1]
シグナルワード
Danger
危険有害性の分類
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2 Oral
ターゲットの組織
Stomach,large intestine,lymph node
保管分類コード
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
39391-10ML:
39391-BULK:
39391-50ML:
39391-VAR:
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資料
Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.
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Which is the suggested EDC concentration and the relative protocol for covalently attach haptens to carrier proteins (e.g. BSA) ?
1 回答-
役に立ちましたか？
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How can I determine the shelf life / expiration / retest date of this product?
1 回答-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf役に立ちましたか？
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 回答-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
役に立ちましたか？
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What is the concentration of the EDC chemical in the 10mL solution?
1 回答-
This product is considered to be a pure/neat EDC material. It has a purity specification of 97% or greater, but it is not a solution of EDC in a solvent.
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