287644

(1R,2R)-(−)-Pseudoephedrine

98%

• 別名: α-(1-Methylaminoethyl)benzyl alcohol, (−)-ψ-Ephedrine, (−)-Pseudoephedrine, (1R,2R)-(−)-2-(Methylamino)-1-phenylpropanol, l-Pseudoephedrine
• 化学式: C₆H₅CH[CH(NHCH₃)CH₃]OH
• CAS番号: 321-97-1
• 分子量: 165.23
• Beilstein: 2803417
• EC Number: 206-292-8
• MDL番号: MFCD00002203
• UNSPSCコード: 12352116
• PubChem Substance ID: 24857283
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 98%
• フォーム: solid
• 光学活性: [α]20/D −51°, c = 0.6 in ethanol
• mp: 118-120 °C (lit.)
• 官能基: amine; hydroxyl; phenyl
• SMILES記法: CN[C@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10+/m1/s1
• InChI Key: KWGRBVOPPLSCSI-SCZZXKLOSA-N

詳細

詳細

(1R,2R)-(-)-Pseudoephedrine is an enantiomer of ephedrine mainly used as a chiral auxiliary for asymmetric synthesis.[1]

アプリケーション

(1R,2R)-(-)-Pseudoephedrine may be used in the preparation of chiral relay ligands, which can catalyze the addition of diethylzinc to aldehydes leading to the corresponding secondary alcohol.[2] The immobilization of pseudoephedrine on Merrifield resin forms a chiral linker, which may be used for the asymmetric alkylation of amides via solid-phase approach.[3]

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H314,H317,H336
• 注意書き: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• ターゲットの組織: Central nervous system
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves