コンテンツへスキップ
Merck

PPARG

peroxisome proliferator-activated receptor gamma

別名:
CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5468) Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(19016) peroxisome proliferator activated receptor gamma
  • Rat(25664) peroxisome proliferator-activated receptor gamma
  • Zebrafish(557037) peroxisome proliferator activated receptor gamma
  • chicken(373928) peroxisome proliferator-activated receptor gamma
  • cow(281993) peroxisome proliferator-activated receptor gamma
  • naked mole-rat(101711078) peroxisome proliferator-activated receptor gamma
  • Goat(100861309) peroxisome proliferator-activated receptor gamma
  • domestic cat(100049014) peroxisome proliferator-activated receptor gamma
  • domestic cat(101095161) peroxisome proliferator-activated receptor gamma
  • domestic guinea pig(100729138) peroxisome proliferator-activated receptor gamma
  • sheep(443513) peroxisome proliferator-activated receptor gamma
  • dog(403606) peroxisome proliferator-activated receptor gamma

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Activator

製品番号
詳細
Species
シグリチゾン, ≥98% (HPLC),
Species
mouse, human
2-(p-クロロフェノキシ)-2-メチルプロピオン酸, 97%,
Species
mouse, human
WY-14643, ,
Species
rat, human, mouse
ベザフィブラート, ≥98%, solid,
Species
mouse, human

Small Molecule - Agonist

製品番号
詳細
Species
ロシグリタゾン, ≥98% (HPLC),
Species
human
ピオグリタゾン 塩酸塩, ≥98% (HPLC),
Species
human
ピオグリタゾン, ,
Species
human
ピオグリタゾン 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
Pioglitazone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
GW9662, >98% (HPLC),
Species
human
トログリタゾン, ≥98% (HPLC),
Species
human
シグリチゾン, ≥98% (HPLC),
Species
mouse, human
GW0742, ≥98% (HPLC),
Species
human
cis-5,8,11,14,17-エイコサペンタエン酸, ≥99%,
Species
mouse, human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-PPAR-gamma Antibody, from rabbit, purified by affinity chromatography,
交差性
canine, feline, human, monkey, mouse, porcine
アプリケーション
immunocytochemistry
western blot
Anti-PPAR-γ antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-PPARγ antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-phospho-PPAR-γ (pSer112) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
Anti-PPAR gamma antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot

Proteins

製品番号
詳細
Species
PPAR, γ ヒト, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
PPAR γ、リガンド結合ドメイン (204-477)、GSTタグ融合 ヒト, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PPARG,
Species
human
MISSION® esiRNA, targeting mouse Pparg,
Species
mouse