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Merck

KCNA3

potassium voltage-gated channel, shaker-related subfamily, member 3

別名:
HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3738) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(16491) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Rat(29731) potassium voltage-gated channel, shaker-related subfamily, member 3
  • cow(525507) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic cat(101092201) potassium voltage-gated channel, shaker-related subfamily, member 3
  • dog(490110) potassium voltage-gated channel, shaker-related subfamily, member 3
  • chicken(404303) potassium voltage-gated channel, shaker-related subfamily, member 3
  • naked mole-rat(101719045) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic guinea pig(100721847) potassium voltage-gated channel, shaker-related subfamily, member 3
  • sheep(101105466) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Domestic Rabbit(100328945) potassium voltage-gated channel, shaker-related subfamily, member 3

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Potassium Channel Kv1.3 Antibody, extracellular domain, Chemicon®, from rabbit,
交差性
human, rat
アプリケーション
flow cytometry
western blot
Anti-KV1.3 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry
Anti-phospho-Kv1.3/KCNA3 (pTyr135) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-KCNA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-Potassium Channel Kv1.3 Antibody, Chemicon®, from rabbit,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Blocker

製品番号
詳細
Species
カリブドトキシン, ≥90% (HPLC),
Species
mouse, rat, human
グアニジン 塩酸塩, for molecular biology, ≥99%,
Species
human
グアニジン 塩酸塩, ≥98%,
Species
human
グアニジン 塩酸塩, ≥99% (titration), organic base and chaeotropic agent,
Species
human
グアニジン 塩酸塩, ,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human KCNA3,
Species
human