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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

別名:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Species:
Human HTR3A (3359), Mouse Htr3a (15561), Rat Htr3a (79246), Domestic Rabbit HTR3A (100009570), chicken HTR3A (428247), domestic guinea pig Htr3a (100135547), Horse HTR3A (100009690), naked mole-rat Htr3a (101714088), sheep HTR3A (101110536), dog HTR3A (489399) ...詳細
UniProtKB ID:
P46098, B4DSY6, G5E986, O60854, Q7KZM7, Q99918, Q9BSZ9
遺伝子ID:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

製品番号
詳細
Species
32473
メトクロプラミド, VETRANAL®, analytical standard,
Species
human
M1824990
メトクロプラミド, European Pharmacopoeia (EP) Reference Standard,
Species
human
BP357
メトクロプラミド 塩酸塩, British Pharmacopoeia (BP) Reference Standard,
Species
human
S1688
SR 57227A, solid,
Species
human
M0763
メトクロプラミド 塩酸塩, solid,
Species
human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
D9190
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
H9523
セロトニン 塩酸塩, powder,
Species
human
H7752
セロトニン・クレアチニン硫酸塩 一水和物, powder,
Species
human
O3639
オンダンセトロン 塩酸塩 二水和物, ≥98% (HPLC), powder,
Species
human
73659
1-(4-クロロフェニル)ピペラジン, ≥98.0% (GC),
Species
rat
1478582
オンダンセトロン 塩酸塩 二水和物, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
HPA069442
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunohistochemistry
ABN1475
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
immunohistochemistry
western blot

Small Molecule - Blocker

製品番号
詳細
Species
T3146
トリミプラミン マレイン酸塩, ≥98% (TLC), powder,
Species
human
Z101
ジメリジン 二塩酸塩, solid,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
F1553
S-(+)-フルオキセチン 塩酸塩, ≥98% (HPLC), solid,
Species
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
F132
フルオキセチン 塩酸塩, solid,
Species
human
R0875
レセルピン, ,
Species
human
S6319
セルトラリン 塩酸塩, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

製品番号
詳細
Species
H8876
5-ヒドロキシインドール-3-酢酸, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

製品番号
詳細
Species
H9772
5-ヒドロキシ-L-トリプトファン, powder,
Species
human

esiRNA

製品番号
詳細
Species
EMU053551
MISSION® esiRNA, targeting mouse Htr3a,
Species
mouse
EHU080571
MISSION® esiRNA, targeting human HTR3A,
Species
human