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Merck

GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1

別名:
GluN1, MRD8, NMDA1, NMDAR1, NR1
Species:
Human GRIN1 (2902), Mouse Grin1 (14810), Rat Grin1 (24408), naked mole-rat Grin1 (101720185), Horse GRIN1 (100059861), chicken GRIN1 (404296), sheep GRIN1 (443281), cow GRIN1 (100336579), domestic guinea pig Grin1 (100301989), dog GRIN1 (494007)
UniProtKB ID:
Q05586, A6NLK7, A6NLR1, C9K0X1, P35437, Q12867, Q12868, Q5VSF3
遺伝子ID:
  • Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1

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Small Molecule - Agonist

製品番号
詳細
Species
S4250
D-セリン, ≥98% (TLC),
Species
human
S2876
スペルミン 四塩酸塩, powder or crystals,
Species
human
T0625
タウリン, ≥99%,
Species
human, rat
C3909
D-シクロセリン, synthetic,
Species
human
M3262
N-メチル-D-アスパラギン酸, ≥98% (TLC), solid,
Species
human, rat

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
A6981
アカンプロサートカルシウム, ≥98% (HPLC), powder,
Species
human
1000554
アカンプロサートカルシウム, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
BP1172
アカンプロサートカルシウム, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
M216
MDL 105,519, ≥98% (HPLC), solid,
Species
rat, human
SML0053
CP-101,606, ≥98% (HPLC),
Species
human
I2892
イフェンプロジル (+)-酒石酸塩, ,
Species
human
A0384
Arcaine sulfate salt, ,
Species
human
A1910
(±)-2-アミノ-4-ホスホノ酪酸, solid,
Species
rat, human

Antibodies

製品番号
詳細
交差性
アプリケーション
SAB2500698
抗NMDAレセプター 1/GRIN1 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse
アプリケーション
ELISA
immunofluorescence
SAB5200546
Monoclonal Anti-Glun1-Nr1 antibody produced in mouse, clone S308-48, purified immunoglobulin,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
immunohistochemistry
western blot
SAB4501301
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4501302
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
western blot
SAB4300405
Anti-GRIN1 (Ab-896) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot

Small Molecule - Blocker

製品番号
詳細
Species
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Species
human
A7127
アグマチン 硫酸塩, ≥97%, powder,
Species
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
T0625
タウリン, ≥99%,
Species
human, rat
P0547
ペンタミジン イセチオン酸塩, powder,
Species
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Species
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

製品番号
詳細
Species
EHU157091
MISSION® esiRNA, targeting human GRIN1,
Species
human
EMU049051
MISSION® esiRNA, targeting mouse Grin1,
Species
mouse