コンテンツへスキップ
Merck

GRIA3

glutamate receptor, ionotropic, AMPA 3

別名:
GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2892) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
  • Mouse(53623) glutamate receptor, ionotropic, AMPA3 (alpha 3)
  • Rat(29628) glutamate receptor, ionotropic, AMPA 3
  • chicken(396138) glutamate receptor, ionotropic, AMPA 3
  • sheep(443273) glutamate receptor, ionotropic, AMPA 3
  • cow(534626) glutamate receptor, ionotrophic, AMPA 3
  • dog(492110) glutamate receptor, ionotropic, AMPA 3
  • Horse(100055136) glutamate receptor, ionotropic, AMPA 3
  • naked mole-rat(101713289) glutamate receptor, ionotropic, AMPA 3
  • domestic cat(101089925) glutamate receptor, ionotropic, AMPA 3
  • Domestic Rabbit(100341980) glutamate receptor, ionotropic, AMPA 3

Custom & Knockdown Gene Products

Small Molecule - Agonist

製品番号
詳細
Species
2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド, ≥98% (HPLC), solid,
Species
human
シクロチアジド, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat
(S)-AMPA, ≥97%,
Species
mouse, human, rat
(アミノメチル)ホスホン酸, 99%,
Species
rat, human

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
CX546, ≥98% (HPLC), solid,
Species
human
ピラセタム, ,
Species
human, rat
シクロチアジド, ,
Species
human, rat
トピラマート, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
トピラマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
GYKI 52466 塩酸塩, solid,
Species
human
ピラセタム, ,
Species
human, rat
CNQX 二ナトリウム塩 水和物, ≥98% (HPLC), solid,
Species
human
NBQX 二ナトリウム塩 水和物, ≥98% (HPLC),
Species
human
(±)-AMPA, solid,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Glutamate Receptor 3 Antibody, clone 3B3, clone 3B3, Chemicon®, from mouse,
交差性
human, monkey, mouse, rat
アプリケーション
immunocytochemistry
immunohistochemistry

western blot
Anti-GRIA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-GRIA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

製品番号
詳細
Species
シクロチアジド, ,
Species
human, rat
キヌレン酸, ≥98%,
Species
rat, human
トピラマート, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
トピラマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
トピラマート, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
シクロチアジド, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GRIA3,
Species
human
MISSION® esiRNA, targeting mouse Gria3,
Species
mouse