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ATP1A1

ATPase, Na+/K+ transporting, alpha 1 polypeptide

別名:
Species:
UniProtKB ID:
遺伝子ID:
  • Human(476) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
  • Mouse(11928) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Rat(24211) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic cat(101083695) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Horse(100034139) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • dog(403992) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • chicken(396530) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • Domestic Rabbit(100302415) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • sheep(443381) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • cow(282144) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • naked mole-rat(101697634) ATPase, Na+/K+ transporting, alpha 1 polypeptide
  • domestic guinea pig(100192382) ATPase, Na+/K+ transporting, alpha 1 polypeptide

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Small Molecule - Activator

製品番号
詳細
Species
ジギトキシゲニン, ,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
モノクロナール抗Na+/K+ ATPアーゼ (α サブユニット) マウス宿主抗体, clone M7-PB-E9, ascites fluid,
交差性
bovine, canine, chicken, human, mouse, pig, sheep
アプリケーション
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
抗Na+/K+ ATPase α-1 抗体 クローン C464.6 ZooMAb® マウス・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
xenopus, canine, human, monkey, mouse, porcine, rabbit, rat, sheep
アプリケーション
immunocytochemistry
immunohistochemistry

western blot
Anti-Na+/K+ ATPase α-1 Antibody, Upstate®, from rabbit,
交差性
bovine, human, rat
アプリケーション
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-phospho-ATP1 α1/Na+K+ ATPase1 (pSer23) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

western blot
Anti-ATP1A1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
メリチン, ≥97% (HPLC), synthetic,
Species
mouse, rat, human
ジギトキシン, ≥92% (HPLC), powder,
Species
human
ジゴキシン, United States Pharmacopeia (USP) Reference Standard,
Species
human
ジギトキシン, United States Pharmacopeia (USP) Reference Standard,
Species
human
Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Proteins

製品番号
詳細
Species
アデノシン 5′-トリホスファターゼ ブタ大脳皮質由来, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
Species

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human ATP1A1,
Species
human
MISSION® esiRNA, targeting mouse Atp1a1,
Species
mouse