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Merck

AGTR1

angiotensin II receptor, type 1

別名:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Species:
Human AGTR1 (185), naked mole-rat Agtr1 (101714068), Domestic Rabbit AGTR1 (100009164), domestic guinea pig Agtr1 (100192325), sheep AGTR1 (443107), dog AGTR1 (403836), chicken AGTR1 (396065), cow AGTR1 (281607), domestic cat AGTR1 (101082936)
UniProtKB ID:
P30556, Q13725
遺伝子ID:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Agonist

製品番号
詳細
Species
A8846
ProteoMass™アンジオテンシンII MALDI-MSスタンダード, vial of 10 nmol,
Species
human
A2900
[Val5]-アンジオテンシンII 酢酸塩 水和物, ≥95% (HPLC), powder,
Species
mouse, human, rat
A6402
[Asn1, Val5]-アンジオテンシン II, ≥97% (HPLC),
Species
mouse, human, rat

Small Molecule - Antagonist

製品番号
詳細
Species
T8949
テルミサルタン, ≥98% (HPLC), solid,
Species
human
SML0142
バルサルタン, ≥98% (HPLC),
Species
human
1708762
バルサルタン, United States Pharmacopeia (USP) Reference Standard,
Species
human
1370462
ロサルタンカリウム, United States Pharmacopeia (USP) Reference Standard,
Species
human
1643419
テルミサルタン, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
AB15552
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
交差性
human, mouse, rat
アプリケーション
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
SAB3500209
抗AGTR1 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
western blot
ZRB2442
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, canine, human, mouse, rat
アプリケーション
affinity binding assay
immunocytochemistry
western blot
SAB2100073
抗AGTR1 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
アプリケーション
western blot
SAB5702971
Anti-AT1R/AGTR1 Antibody, clone 8W6G0, Rabbit Monoclonal, ,
交差性
human
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
C4042
カプトプリル, ≥98% (HPLC), powder,
Species
human, rat
547905
2,2′:5′,2″:5″,2″′-クアテルチオフェン, 96%,
Species
human, rat, mouse

Proteins

製品番号
詳細
Species
HTS064M
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human

esiRNA

製品番号
詳細
Species
EHU090121
MISSION® esiRNA, targeting human AGTR1,
Species
human