1327000

Hydroxychloroquine sulfate

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: Hydroxychloroquine sulfate, 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
• Formula empirica (notazione di Hill): C₁₈H₂₆ClN₃O · H₂SO₄
• Numero CAS: 747-36-4
• Peso molecolare: 433.95
• Numero CE: 212-019-3
• Numero MDL: MFCD00078203
• Codice UNSPSC: 41116107
• ID PubChem: 329750122
• NACRES: NA.24

Proprietà

• Origine biologica: synthetic
• Grado: pharmaceutical primary standard
• agenzia: USP
• Famiglia di API: hydroxychloroquine
• Confezionamento: pkg of 200 mg
• Produttore/marchio commerciale: USP
• Condizioni di stoccaggio: protect from light
• Colore: white to off-white
• pH: 3.5-5.5 (1% in aqueous solution, pH <6.0)
• Punto di fusione: 388.4 °F (198°C; 240°C)
• Solubilità: chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble; water: soluble
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4); JCBIVZZPXRZKTI-UHFFFAOYSA-N
• Informazioni sul gene: human ... TLR7(51284) , TLR9(54106)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Hydroxychloroquine Sulfate is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.

Applicazioni

Hydroxychloroquine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Hydroxychloroquine Sulfate Tablets
• Hydroxychloroquine Sulfate Compounded Oral Suspension
• Chloroquine Phosphate

Azioni biochim/fisiol

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302,H315,H319
• Consigli di prudenza: P301 + P312 + P330 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable