V4890

Vindesine sulfate salt hydrate

≥95% (HPLC)

• Sinonimo/i: 3-(Aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine sulfate salt hydrate, Desacetylvinblastine amide sulfate salt hydrate
• Formula empirica (notazione di Hill): C₄₃H₅₅N₅O₇ · H₂SO₄ · xH₂O
• Numero CAS: 59917-39-4
• Peso molecolare: 852.00 (anhydrous basis)
• Codice UNSPSC: 12352200
• ID PubChem: 329829055
• NACRES: NA.77

Proprietà

• Saggio: ≥95% (HPLC)
• Stato: powder
• Colore: off-white to light yellow
• Solubilità: deionized water: ≥50 mg/mL
• Ideatore: Eli Lilly
• Temperatura di conservazione: −20°C
• Stringa SMILE: O.OS(O)(=O)=O.CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@H]7[C@](O)([C@H](O)[C@]8(CC)C=CC[N@H]9CC[C@]67[C@H]89)C(N)=O)C1
• InChI: 1S/C43H55N5O7.H2O4S.H2O/c1-6-39(52)21-25-22-42(38(51)55-5,33-27(13-17-47(23-25)24-39)26-11-8-9-12-30(26)45-33)29-19-28-31(20-32(29)54-4)46(3)35-41(28)15-18-48-16-10-14-40(7-2,34(41)48)36(49)43(35,53)37(44)50;1-5(2,3)4;/h8-12,14,19-20,25,34-36,45,49,52-53H,6-7,13,15-18,21-24H2,1-5H3,(H2,44,50);(H2,1,2,3,4);1H2/t25-,34+,35-,36-,39+,40-,41-,42+,43+;;/m1../s1; TUDLKTILIBRXNU-RIHOAIHNSA-N

Descrizione

Azioni biochim/fisiol

Microtubule inhibitor

Microtubule inhibitor. Vindesine binds to and stabilizes tubulin, thereby preventing tubulin polymerization, preventing mitosis, and arresting cells in metaphase.

Caratteristiche e vantaggi

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable