P7036

Parathyroid hormone human

≥92% (HPLC), powder

• Sinonimo/i: PTH, Parathormone
• Formula empirica (notazione di Hill): C₄₀₈H₆₇₄N₁₂₆O₁₂₆S₂
• Numero CAS: 68893-82-3
• Peso molecolare: 9424.62
• Numero MDL: MFCD00081830
• Codice UNSPSC: 51111800
• NACRES: NA.32

Proprietà

• Origine biologica: synthetic (organic)
• Livello qualitativo: 200
• Sterilità: non-sterile
• Saggio: ≥92% (HPLC)
• Stato: powder
• Composizione: Peptide content, ≥70%
• Solubilità: water: 1 mg/mL, clear, colorless
• N° accesso UniProt: P01270
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... PTH(5741)

Descrizione

Amino Acid Sequence

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln

Descrizione generale

Parathyroid hormone (PTH) is a circulating hormone secreted from the parathyroid gland. This hormone is synthesized as a pre-pro hormone. PTH is composed of binding regions that have a high affinity to a receptor and functional domains that interact with the receptors to initiate an intracellular signaling cascade.

Applicazioni

Parathyroid hormone human has been used to incubate mature human adipocytes.

Azioni biochim/fisiol

Parathyroid hormone (PTH) exerts its effects on bone and kidney cells. This hormone plays a role in calcium homeostasis. PTH is secreted from the chief cells of the parathyroid gland in response to low extracellular calcium levels or higher levels of extracellular phosphate. PTH deficiency or excess PTH are associated with hypoparathyroidism and hyperparathyroidism, respectively.

Componenti

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable