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P7002

Sigma-Aldrich

Phospho(enol)pyruvic acid trisodium salt hydrate

≥97% (enzymatic), powder

Sinonimo/i:

2-(Phosphonooxy)-2-propenoic acid trisodium salt, PEP

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100 MG
114,00 €
250 MG
198,00 €
500 MG
346,00 €
1 G
593,00 €
5 G
1.057,00 €
25 G
5.750,00 €

114,00 €


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Scegli un formato

Cambia visualizzazione
100 MG
114,00 €
250 MG
198,00 €
500 MG
346,00 €
1 G
593,00 €
5 G
1.057,00 €
25 G
5.750,00 €

About This Item

Formula condensata:
C3H2O6PNa3 · x H2O
Numero CAS:
Peso molecolare:
233.99 (anhydrous basis)
Numero MDL:
Codice UNSPSC:
12352204
ID PubChem:
NACRES:
NA.32

114,00 €


Per informazioni sulla disponibilità, contatta il Servizio Clienti.

Nome del prodotto

Phospho(enol)pyruvic acid trisodium salt hydrate, ≥97% (enzymatic)

Livello qualitativo

Saggio

≥97% (enzymatic)

Stato

powder

Solubilità

water: 100 mg/mL, clear to slightly hazy, colorless to very faintly yellow

Temperatura di conservazione

−20°C

Stringa SMILE

[Na].OC(=O)C(=C)OP(O)(O)=O

InChI

1S/C3H5O6P.Na.H/c1-2(3(4)5)9-10(6,7)8;;/h1H2,(H,4,5)(H2,6,7,8);;
KZPUEZVJSLLABH-UHFFFAOYSA-N

Applicazioni

Phospho(enol)pyruvic acid trisodium salt hydrate has been used in:
  • several enzyme activity assays, such as PRPP synthetase (PRPPS) assay[1], ribokinase (RK) assay[1], adenine phosphoribosyltransferase (APRT) assay[1]
  • in the reaction mixture for enzyme kinetic assay to determine platelet-derived growth factor receptor α (PDGFRA) kinetic parameters[2]
  • as a component in buffer B to react with adenosine diphosphate (ADP) to form adenosine triphosphate (ATP) for energy charge measurement[3]

Azioni biochim/fisiol

Phosphoenolpyruvic acid plays a major role in the initial step of glycolysis by acting as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase.[4]
Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogenesis. In glycolysis, PEP is metabolized by pyruvate kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Casimir Ledoux Sofeu et al.
PLoS neglected tropical diseases, 12(9), e0006597-e0006597 (2018-09-07)
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Structural and biochemical studies of the PDGFRA kinase domain
Liang L, et al.
Biochemical and Biophysical Research Communications, 477(4), 667-672 (2016)
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Faraday discussions, 218(0), 303-316 (2019-05-28)
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