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P3761

Sigma-Aldrich

Pentobarbital sodium salt

Sinonimo/i:

5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxohexahydropyrimidine, Nembutal

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About This Item

Formula empirica (notazione di Hill):
C11H17N2NaO3
Numero CAS:
Peso molecolare:
248.25
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
Per informazioni sul prodotto P3761, contatta il rappresentante o rivenditore Merck di zona. Contatta l'Assistenza Tecnica.

Stato

powder

Livello qualitativo

Controllo stupefacenti

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Solubilità

H2O: soluble
alcohol: soluble

Stringa SMILE

[Na].CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3.Na.H/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);;
PGOYUXGHADTNIB-UHFFFAOYSA-N

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Applicazioni

Pentobarbital sodium salt has been used as an anesthetic in rats[1] and mice[2][3] prior to various in vitro studies.

Azioni biochim/fisiol

Pentobarbital (PB) is a barbiturate and a ligand of the γ-aminobutyric acid subtype A (GABAA) receptor.[4] It is a sedative anesthetic[5] majorly used in rodent euthanasia.[4] Pentobarbital possesses hypnotic functionality[4] and muscle relaxing properties.[5] It enhances GABAergic activity.[6] Intraperitoneal injection of PB may result in loss of righting reflex (LORR) and heartbeat cessation.[5]

Pittogrammi

Skull and crossbonesHealth hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Domande

1–5 di 5 domande  
  1. Is Pentobarbital sodium salt available as a solution?

    1 risposta
    1. We do not offer a solution of pentobarbital as it is not stable as a solution.

      Utile?

  2. How can I store my solution of Pentobarbital sodium salt, Product P3761?

    1 risposta
    1. Solutions of the sodium salt are typically pH 9.0 - 11.0 (BP/USP). If the pH is lowered, the free acid will precipitate from solution. Solutions decompose on standing, the decomposition being accelerated at higher temperatures.  We recommend to make solutions fresh.

      Utile?

  3. What is the Department of Transportation shipping information for this product?

    1 risposta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Utile?

  4. How can I solubilize Pentobarbital sodium salt, Product P3761?

    1 risposta
    1. This product is soluble in water (50 mg/ml), with heat and sonication as needed, yielding a clear to slightly hazy, colorless solution.

      Utile?

  5. What is the shelf life for Pentobarbital sodium salt, Product P3761?

    1 risposta
    1. Product No. P3761 has a retest date of 3 years from date of manufacture.

      Utile?

Recensioni

Nessuna valutazione

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