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Documenti fondamentali

O2501

Sigma-Aldrich

Ornithine Transcarbamylase from Streptococcus faecalis

lyophilized powder, ≥300 units/mg protein

Sinonimo/i:

Carbamoylphosphate:L-Ornithine Carbamoyltransferase, OTCase, Ornithine Carbamoyl Transferase

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About This Item

Numero CAS:
Classificazione EC (Enzyme Commission):
Numero CE:
Numero MDL:
Codice UNSPSC:
12352204

Stato

lyophilized powder

Livello qualitativo

Attività specifica

≥300 units/mg protein

Composizione

Protein, ≥65% Lowry

Temperatura di conservazione

−20°C

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Azioni biochim/fisiol

Mutations in ornithine transcarbamylase cause Ornithine transcarbamylase deficiency which prevents the clearance of the byproduct ammonia leading to hyperammonemia.

Definizione di unità

One unit will form 1.0 μmole of citrulline from ornithine and carbamyl phosphate per min at pH 8.5 at 37 °C.

Stato fisico

Lyophilized powder contains Tris buffer salts

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Jon Jerlström-Hultqvist et al.
Eukaryotic cell, 11(7), 864-873 (2012-05-23)
In recent years, proteomics has come of age with the development of efficient tools for purification, identification, and characterization of gene products predicted by genome projects. The intestinal protozoan Giardia intestinalis can be transfected, but there is only a limited
Wataru Takagi et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 161(4), 331-340 (2012-01-10)
Cartilaginous fish comprise two subclasses, the Holocephali (chimaeras) and Elasmobranchii (sharks, skates and rays). Little is known about osmoregulatory mechanisms in holocephalan fishes except that they conduct urea-based osmoregulation, as in elasmobranchs. In the present study, we examined the ornithine
Luis Mariano Polo et al.
PloS one, 7(2), e31528-e31528 (2012-03-01)
Transcarbamylases reversibly transfer a carbamyl group from carbamylphosphate (CP) to an amine. Although aspartate transcarbamylase and ornithine transcarbamylase (OTC) are well characterized, little was known about putrescine transcarbamylase (PTC), the enzyme that generates CP for ATP production in the fermentative
Taiichi Wakiya et al.
Molecular genetics and metabolism, 105(3), 404-407 (2012-01-24)
There are no objective and concrete guidelines for the management of Ornithine transcarbamylase deficiency (OTCD). Based on previous findings, we hypothesized that patients with OTCD have a low Ornithine transcarbamylase (OTC) activity in the liver, and therefore it would be
Jing Wang et al.
Molecular genetics and metabolism, 106(2), 221-230 (2012-04-13)
Oligonucleotide array-based comparative genomic hybridization (aCGH) targeted to coding exons of genes of interest has been proven to be a valuable diagnostic tool to complement with Sanger sequencing for the detection of large deletions/duplications. We have developed a custom designed

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