L2506

β-Lactoglobulin from bovine milk

≥85% (PAGE), lyophilized powder

• Sinonimo/i: β-LG, Bos d 5, beta-LG
• Numero CAS: 9045-23-2
• Numero CE: 232-928-9
• Numero MDL: MFCD00130635
• Codice UNSPSC: 12352202
• NACRES: NA.61

Proprietà

• Origine biologica: bovine milk
• Saggio: ≥85% (PAGE)
• Stato: lyophilized powder
• tecniche: titration: suitable
• N° accesso UniProt: P02754
• Temperatura di conservazione: 2-8°C
• Informazioni sul gene: bovine ... LGB(280838)

Descrizione

Descrizione generale

β-Lactoglobulin plays a key role in immune response and modulates IgM levels and cell proliferation.[1] β-Lactoglobulin from bovine is a model system for protein folding studies and denaturation kinetics.[2] Polymorphisms in the β-lactoglobulin modulates bovine milk production and composition.[3]

A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da,. It has an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.[4]

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.[5]

Applicazioni

β-Lactoglobulin from bovine milk has been used:

• for the generation of calibration curve for protein solubility index[6]
• in acid-base titration[7]
• as a standard for surface hydrophobicity analysis[8]

β-Lactoglobulin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.[9]

Qualità

Contains β-lactoglobulins A and B which can be isolated chromatographically.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)