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Merck
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Documenti

I9759

Sigma-Aldrich

Ile-Pro-Ile

≥97% (HPLC)

Sinonimo/i:

Diprotin A

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About This Item

Formula empirica (notazione di Hill):
C17H31N3O4
Numero CAS:
90614-48-5
Peso molecolare:
341.45
Numero MDL:
MFCD00038707
Codice UNSPSC:
51111800
ID PubChem:
24896160
NACRES:
NA.77

Saggio

≥97% (HPLC)

Forma fisica

powder

Solubilità

water: 1 mg/mL, clear, colorless

Temperatura di conservazione

−20°C

Stringa SMILE

CCC(C)C(N)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(O)=O

InChI

1S/C17H31N3O4/c1-5-10(3)13(18)16(22)20-9-7-8-12(20)15(21)19-14(17(23)24)11(4)6-2/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)
JNTMAZFVYNDPLB-UHFFFAOYSA-N

Amino Acid Sequence

Ile-Pro-Ile

Applicazioni

Ile-Pro-Ile has been used as a supplement for blood collection for hormone measurement and used in Islets cell culture to stabilize glucagon-like peptide-1 (GLP-1). It has also been used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection.

Azioni biochim/fisiol

Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.

Caratteristiche e vantaggi

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Y0001812

Sitagliptin phosphate monohydrate

DPP4 Activity Assay Kit sufficient for 100 fluorometric tests

Sigma-Aldrich

MAK088

DPP4 Activity Assay Kit

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly

Sigma-Aldrich

F7131

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly

Sitagliptin Phosphate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1857

Sitagliptin Phosphate

F Samuel van Nierop et al.
Clinical nutrition (Edinburgh, Scotland), 36(6), 1615-1620 (2016-10-25)
Bile acids (BA) are pleiotropic hormones affecting glucose and lipid metabolism. The physiochemical properties of different BA species affect their enterohepatic dynamics and their affinity for bile acid receptors. The BA pool composition is altered in patients with type 2
Gemma Pujadas et al.
Molecular metabolism, 39, 101008-101008 (2020-05-12)
Glucose-dependent insulinotropic polypeptide (GIP) conveys information from ingested nutrients to peripheral tissues, signaling energy availability. The GIP Receptor (GIPR) is also expressed in the bone marrow, notably in cells of the myeloid lineage. However, the importance of gain and loss
Effect of gonadotropin-inhibitory hormone on luteinizing hormone secretion in humans
George JT, et al.
Clinical Endocrinology, 86(5), 731-738 (2017)
Pádraigín A Harnedy et al.
Food research international (Ottawa, Ont.), 106, 598-606 (2018-03-28)
Large quantities of low-value protein rich co-products, such as salmon skin and trimmings, are generated annually. These co-products can be upgraded to high-value functional ingredients. The aim of this study was to assess the antidiabetic potential of salmon skin gelatin
Pancreatic alpha cell-derived glucagon-related peptides are required for beta cell adaptation and glucose homeostasis
Traub S, et al.
Cell Reports, 18(13), 3192-3203 (2017)
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