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G8279

Sigma-Aldrich

Gum guaiac

crude colorimetric peroxidase substrate

Sinonimo/i:

Guaiac, Guaiacum, Resin guaiac

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About This Item

Numero CAS:
Numero CE:
Numero MDL:
Codice UNSPSC:
12352201

Stato

powder

Punto di fusione

85 °C (dec.) (lit.)

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Applicazioni

Gum guaiac is a tree resin and crude source of 2,5-di-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran (α-guaiaconic acid).[1] The phenolic α-guaiaconic acid acts as a colorimetric peroxidase substrate.[2][3][4] When reacted with an organic or inorganic oxidizing agent, the α-guaiaconic acid is oxidized to a blue-colored quinone. The guaiac reaction has been used to detect trace amounts of heme from hemoglobin in the presence of peroxide.
The Nobles test can be performed using 67% (w/v) gum guaiac diluted in 96% ethanol to analyze the level of extracellular oxidase production [5]

Altre note

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Mechanism of Oxidation in the Plant. Part II: An Investigation of Substances which are capable of behaving as Peroxydases.
P H Gallagher
The Biochemical journal, 18(1), 29-38 (1924-01-01)
C K Palmer et al.
British journal of cancer, 110(7), 1705-1711 (2014-03-13)
Screening for bowel cancer using the guaiac faecal occult blood test offered by the NHS Bowel Cancer Screening Programme (BCSP) is taken up by 54% of the eligible population. Uptake ranges from 35% in the most to 61% in the
S Webendörfer et al.
Deutsche medizinische Wochenschrift (1946), 139(3), 79-83 (2013-10-04)
If the diagnosis is made early the cure rate of bowel cancer is more than 90 %. Occupational preventative medical care required by law and carried out by company physicians can be supplemented by a medical consultation and by simple screenings
Hermann Brenner et al.
European journal of cancer (Oxford, England : 1990), 49(14), 3049-3054 (2013-05-28)
There is increasing evidence that faecal immunochemical tests (FITs) for haemoglobin offer a number of advantages over traditional guaiac based faecal occult blood tests (gFOBTs). However, evidence on diagnostic performance from direct comparisons with colonoscopy findings in all participants in
Hermann Brenner et al.
International journal of cancer, 134(12), 2927-2934 (2014-01-01)
Guaiac-based fecal occult blood tests (gFOBTs) are the most commonly applied tests for colorectal cancer screening globally but have relatively poor sensitivity to detect colorectal neoplasms. Men have higher prevalences of colorectal neoplasms than women. In case of a positive

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