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G1506

Sigma-Aldrich

Guanylyl(3′→5′)cytidine ammonium salt

Sinonimo/i:

GpC

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About This Item

Formula condensata:
C19H25N8O12P · NH3
Numero CAS:
98046-67-4
Peso molecolare:
605.45
Numero MDL:
MFCD00058649
Codice UNSPSC:
41106305
ID PubChem:
24895064

Forma fisica

solid

Temperatura di conservazione

−20°C

Stringa SMILE

N.NC1=NC(=O)c2ncn(C3OC(CO)C(OP(O)(=O)OCC4OC(C(O)C4O)N5C=CC(N)=NC5=O)C3O)c2N1

InChI

1S/C19H25N8O12P.H3N/c20-8-1-2-26(19(33)23-8)16-11(30)10(29)7(38-16)4-36-40(34,35)39-13-6(3-28)37-17(12(13)31)27-5-22-9-14(27)24-18(21)25-15(9)32;/h1-2,5-7,10-13,16-17,28-31H,3-4H2,(H,34,35)(H2,20,23,33)(H3,21,24,25,32);1H3
PPSONIOCBRREER-UHFFFAOYSA-N

Applicazioni

Guanylyl(3′5′)cytidine is an oligonucleotide pyrimidine dimer used as a substrate to study the specificity and kinetics of various RNases such as RNase T1 and its mutations.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Yang Wang et al.
Nature communications, 12(1), 1247-1247 (2021-02-25)
Extensive epigenetic reprogramming occurs during preimplantation embryo development. However, it remains largely unclear how the drastic epigenetic reprogramming contributes to transcriptional regulatory network during this period. Here, we develop a single-cell multiomics sequencing technology (scNOMeRe-seq) that enables profiling of genome-wide
Francisco Requena et al.
Scientific reports, 9(1), 8140-8140 (2019-06-01)
Recent technical advances highlight that to understand mammalian development and human disease we need to consider transcriptional and epigenetic cell-to-cell differences within cell populations. This is particularly important in key areas of biomedicine like stem cell differentiation and intratumor heterogeneity.
Snawar Hussain et al.
Acta tropica, 173, 136-146 (2017-06-14)
Zika virus is a zoonotic pathogen, which have made frequent incursion into the human population in Africa and South East Asia over the course of several decades but never reached to the pandemic proportions until the most recent outbreak. Viruses
Elena Loreti et al.
Plant physiology, 182(1), 287-300 (2019-07-31)
In plants, hypoxia can be induced by submergence, and the lack of oxygen impairs mitochondrial respiration, thus affecting the plant's energy status. Hypoxia has major effects on gene expression; these changes induce key responses that help meet the needs of
Holger Kruse et al.
Journal of chemical theory and computation, 15(1), 95-115 (2018-11-30)
The stacking energies of 10 unique B-DNA base-pair steps were calculated with highly accurate quantum chemistry and used as reference values in a thorough benchmark of (dispersion-corrected) DFT, wave function methods, tight-binding methods, and different force fields, including charge variants
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