C2800

Cholesteryl phenylacetate

≥98% (HPLC; detection at 258 nm)

• Sinonimo/i: 3β-Hydroxy-5-cholestene 3-phenylacetate, 5-Cholesten-3β-ol 3-phenylacetate
• Formula empirica (notazione di Hill): C₃₅H₅₂O₂
• Numero CAS: 33998-26-4
• Peso molecolare: 504.79
• Numero CE: 251-781-1
• Numero MDL: MFCD00021140
• Codice UNSPSC: 12352211
• ID PubChem: 24892533
• NACRES: NA.77

Proprietà

• Origine biologica: synthetic (organic)
• Saggio: ≥98% (HPLC; detection at 258 nm)
• Stato: crystalline powder
• Gruppo funzionale: ester
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=C(O[C@@H]1CC2=CC[C@]3([H])[C@@](CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)C)([H])[C@@]2(C)CC1)CC5=CC=CC=C5
• InChI: 1S/C35H52O2/c1-24(2)10-9-11-25(3)30-16-17-31-29-15-14-27-23-28(37-33(36)22-26-12-7-6-8-13-26)18-20-34(27,4)32(29)19-21-35(30,31)5/h6-8,12-14,24-25,28-32H,9-11,15-23H2,1-5H3/t25-,28?,29?,30?,31?,32?,34?,35?/m1/s1; JHFRODPXYCPTCM-ZTUKSAGPSA-N

Descrizione

Azioni biochim/fisiol

Cholesteryl phenylacetate is a cholesterol ester found associated with the neutral core of low density lipoprotein. Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.[1] The enzyme acid cholesteryl ester hydrolase is responsible for the hydrolysis of cholesteryl esters; a defective enzyme can result in the formation of atherosclerotic lesions in humans.[2]

Nota sulla preparazione

Cholesteryl phenylacetate yields clear, colorless solution in chloroform at 50 mg/ml.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)