AC-0344

GRIA2 (EP387) Rabbit Monoclonal Primary Antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Forma dell’anticorpo: Ig fraction of antiserum
• Clone: monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Forma fisica: buffered aqueous solution
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: (cytoplasm/membrane)

Descrizione

Descrizione generale

Glutamate receptor 2 (GRIA2) is a ligand-gated ion channel that uses L-glutamate for excitatory synaptic transmission expressed in the central nervous system. A recent gene expression profiling study reported >100 fold GRIA2 induction in solitary fibrous tumors compared with control tissues. Immunohistochemistry studies demonstrated GRIA2 positivity in the majority of solitary fibrous tumors (64-86%). Its diagnostic performance yields 64% sensitivity, 92% specificity, with 41% and 97% positive and negative predictive value, respectively for the differential diagnosis of solitary fibrous tumors versus other mesenchymal soft tissue tumors. GRIA2 may be a useful marker to identify STAT6-negative solitary fibrous tumors.

Qualità

IVD

IVD

IVD

RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1%BSA and &< 0.1% Sodium Azide

Altre note

For a copy of the IFU and CofA contact IVDorder@ABCAM.com

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable