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38790

Sigma-Aldrich

(±)-Pinostrobin

≥99.0% (TLC)

Sinonimo/i:

(RS)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one

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About This Item

Formula empirica (notazione di Hill):
C16H14O4
Numero CAS:
Peso molecolare:
270.28
Numero MDL:
Codice UNSPSC:
12352106
ID PubChem:
NACRES:
NA.25

Saggio

≥99.0% (TLC)

Stringa SMILE

COc1cc(O)c2C(=O)CC(Oc2c1)c3ccccc3

InChI

1S/C16H14O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-8,14,17H,9H2,1H3
ORJDDOBAOGKRJV-UHFFFAOYSA-N

Applicazioni

(±)-Pinostrobin, a chiral flavonoid (±), may be used in the development of analytical methods for separation of its individual enantiomers. Pinostrobin may be used to study its neuroprotective antioxidant effects.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Quercetin ≥95% (HPLC), solid

Sigma-Aldrich

Q4951

Quercetin

Alka Jaudan et al.
PloS one, 13(2), e0191523-e0191523 (2018-02-09)
Pinostrobin (PN) is a naturally occurring dietary bioflavonoid, found in various medicinal herbs/plants. Though anti-cancer potential of many such similar constituents has been demonstrated, critical biochemical targets and exact mechanism for their apoptosis-inducing actions have not been fully elucidated. The
Monika Asztemborska et al.
Electrophoresis, 24(15), 2527-2531 (2003-08-06)
Micellar electrokinetic chromatography (MEKC) was applied for enantioseparation of selected flavanones, including naringin, hesperidin, neohesperidin, naringenin, hesperetin, pinostrobin, isosakuranetin, eriodictyol, and homoeriodictyol. gamma-Cyclodextrin (gamma-CD) and sodium cholate (SCh) were used as chiral modifiers inducing enantioselectivity to the background electrolyte. From
Yan-Fang Xian et al.
Cellular and molecular neurobiology, 32(8), 1223-1230 (2012-05-09)
Beta-Amyloid peptide (Aβ), a major protein component of brain senile plaques in Alzheimer's disease (AD), has been considered as a critical cause in the pathogenesis of AD. Pinostrobin, a potent flavonoid inducer, is the major and most active ingredient of
Stereospecific analytical method development and preliminary in vivo pharmacokinetic characterization of pinostrobin in the rat.
Sayre CL, Zhang Y, Martinez SE, et al.
Biomedical Chromatography (2012)
Karen J Marsh et al.
Phytochemistry, 160, 31-39 (2019-01-27)
A group of plant specialised metabolites (PSMs) collectively known as unsubstituted B-ring flavanones (UBFs) have previously been found in the foliage of some species from the genus Eucalyptus L'Hér. (Myrtaceae), specifically from the subgenus Eucalyptus (monocalypts). Captive feeding studies using

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